Bisphosphonates

Bisphosphonates are a group of traditional, non hormonal drugs used to treat osteoporosis. Bisphosphonates inhibits bone loss and therefore maintains bone density, it may even increase bone density in some individuals.

Members of the Biphosphonate Family

There are several members in the biphosphonate family. These are (generic names):

• Alendronate
• Clodronate
• Etidronate
• Pamidronate
• Tiludronate

Some of these bisphosphonates are taken once daily, some can be taken once weekly.

How to Take Bisphosphonates

Bisphosphonates interacts with calcium salts, mineral supplements, such as iron and magnesium, and antacids. These compounds stops the bisphosphonates from being absorbed into the body, therefore, your biphosphonate tablet would not work to its full potential in stopping bone loss.

Here is a guide on how to take bisphosphonates correctly:

1. Take your biphosphonate tablet first thing in the morning when you wake up.
2. Take your biphosphonate tablet on an empty stomach - no breakfast, no juice, no tea, no coffee - especially with milk.
3. Take your biphosphonate tablet with a full glass of water.
4. Remain upright for at least 30 minutes after taking your tablet (this prevents the tablet from coming up the esophagus or food pipe).
5. Don't eat or drink anything (except water) for at least 30 minutes or 2 hours after taking your tablet (depending on the type of biphosphonate you take).

Side Effects

The most common side effect of biphosphonate tablets are:

• nausea
• vomiting
• diarrhoea
• abdominal pain
• muscle pain or soreness

However, if you experience pain when you swallow, or new or worsening heartburn, you should see your doctor immediately as the bisphosphonates may be causing inflammation or damage to your esophagus (esophagitis or esophageal erosions or ulcers). This side effect occurs infrequently, but it's always better to get it checked out and exclude it as the cause of the heartburn or pain when swallowing.

The information provided is intended solely for general information and is NOT to replace advice from your physician and should NOT be relied upon for any diagnosis, treatment or cure. Always speak with your doctor before starting any new medications.